Fildena 150mg contains sildenafil citrate, which is a phosphodiesterase type 5 (PDE5) inhibitor. Here's how it works:
Mechanism of Action: When a man is sexually stimulated, nitric oxide is released into the erectile tissue of the penis. This nitric oxide activates an enzyme called guanylate cyclase, which in turn increases levels of cyclic guanosine monophosphate (cGMP).
Relaxation of Blood Vessels: Increased cGMP levels cause the smooth muscles in the blood vessels of the penis to relax. This relaxation allows blood to flow into the penile arteries, resulting in an erection.
Role of PDE5: Normally, cGMP is broken down by the enzyme PDE5, leading to a decrease in blood flow into the penis and the loss of an erection. Sildenafil citrate in Fildena 150mg inhibits PDE5, allowing cGMP to accumulate and persist longer in the penis during sexual stimulation.
Enhanced Blood Flow: By blocking PDE5 and maintaining higher levels of cGMP, Fildena 150mg promotes increased blood flow into the penis, facilitating a stronger and longer-lasting erection suitable for sexual intercourse.
Requirement for Sexual Stimulation: It's important to note that Fildena 150mg requires sexual arousal or stimulation to be effective. Without sexual stimulation, sildenafil citrate will not produce an erection.
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